Building on lessons that emerged through the UNDP Anti-Corruption and Integrity in the Arab Countries (ACIAC) programme and regional expert group consultations in 2015–16, UNDP developed a Conceptual Framework for Corruption Risk Assessment at Sectoral Level in 2016. Through the framework, UNDP has supported several countries to customise and test a targeted approach to corruption prevention, equipping partners with the conceptual underpinnings to focus on corruption as a starting point for more comprehensive governance reforms. This 2021 case study outlines the process, results, enabling factors, and lessons learned from the initial phase (2016–2018) of implementing a Corruption Risk Assessment in the health sector in Tunisia.